Complex of a human FOXC2 protein and a FOXC2-interacting protein
US7217692B2 · kind B2 · utility
3Cited by
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1Claims
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Key dates
| Filing date | Jan 28, 2003 |
| Grant date | May 15, 2007 |
| Priority date | — |
| Expiry date | Jan 28, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to complexes of the FOXC2 protein with other proteins, in particular complexes of FOXC2 with proteins designated p621, NOLP, HSC71, FTP3, CLH1, and Kinase A Anchor Protein 84/149 (AKAP). The protein complexes can be used in methods of identifying agents useful for the treatment of medical conditions that can be treated by modulated FOXC2 activity, such as obesity, hypertriglyceridemia, diet-induced insulin resistance, and/or type 2 diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.