Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives
US7217715B2 · kind B2 · utility
1Cited by
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18Claims
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Key dates
| Filing date | Sep 13, 2005 |
| Grant date | May 15, 2007 |
| Priority date | — |
| Expiry date | Sep 13, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a substituted-pyrimidone derivative represented by formula (I) or a salt thereof:wherein X, Y, R1, R2, R3, R4, R5, n, p and q are as described herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.