Antibodies that recognize the 85P1B3 protein useful in treatment and detection of cancer

US7217799B2 · kind B2 · utility

Assignee

• Latency, LLC · US

Inventors

• Arthur B. Raitano · Los Angeles, US
• Mary Faris · Los Angeles, US
• Rene S. Hubert · Los Angeles, US
• Daniel Afar · Santa Monica, US
• Wangmao Ge · Tampa, US
• Pia M. Challita-Eid · Calabasas, US
• Aya Jakobovits · Beverly Hills, US

Key dates

• Filing date: Aug 28, 2001
• Grant date: May 15, 2007
• Expiry date: Aug 28, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/47
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A novel gene (designated 85P1B3) and its encoded protein are described. While 85P1B3 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 85P1B3 provides a diagnostic and/or therapeutic target for cancers. The 85P1B3 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.