System for regulating fluid flowing through chromatographic column
US7219532B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 26, 2005 |
| Grant date | May 22, 2007 |
| Priority date | — |
| Expiry date | Nov 11, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/8693
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are systems and methods that include a sampling device, a chromatographic column, and a transfer line through which a fluid containing analytes to be measured are communicated from the sampling device to the column. The pressure at which the fluid containing the analytes is applied at the inlet of the transfer line is adjusted as the temperature of the column increases in accordance with certain relationships in order to maintain a substantially constant flow rate or velocity for the fluid exiting the column. In this way, the system compensates for changes in the viscosity of the fluid flowing through the column that result from changes in the column temperature.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.