Patent · US Expired

Preparation of factor XIIIa by gene manipulation

US7220556B1 · kind B1 · utility

0Cited by

2References

37Claims

0Family size

Assignee

ZLB Behring AG · CH

Inventors

Ulrich Grundmann · Lahntal, DE
Egon Amann · Marburg, DE
Gerd Zettlmeissl · Lahntal, DE

Key dates

Filing date	Jun 2, 1995
Grant date	May 22, 2007
Priority date	—
Expiry date	Jun 2, 2015

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/91085
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The cDNA which codes for factor XIIIa has been isolated using a cDNA bank from human placenta and probes constructed on the basis of the amino acid sequence of factor XIIIa peptide fragments. It is possible with this cDNA not only to obtain factor XIIIa by gene manipulation in high purity but also to prepare diagnostic aids which permit the analysis of genetic factor XIIIa defects. Furthermore, it is possible on the basis of the amino acid sequence to prepare antibodies which are suitable for diagnostic aids and antibody columns.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.