Patent · US Expired

Automated immunoassay cassette, apparatus and method

US7220595B2 · kind B2 · utility

13Cited by
37References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 6, 2003
Grant dateMay 22, 2007
Priority date
Expiry dateMay 4, 2025

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/81
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An immunoassay cassette, apparatus, and method for detecting an analyte in a liquid body-fluid sample are disclosed. The cassette has a body and a support mounted on the body, for movement toward and away from a sample transfer position. Sample supplied to a sample well in the cassette body is taken up by a reagent reservoir containing a first reagent composition effective to form a modified sample. The support provides a reagent strip having a transfer zone that is brought into contact with the reservoir, when the support is in the transfer position, a detection zone located downstream of the transfer zone, and a second reagent composition effective to react with the modified sample to form a detectable analyte-dependent product. By controlling movement of the support, volume and rate of sample flow from the reservoir to the strip can be controlled to optimize and/or standardize sample-transfer conditions in the assay.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.