Mono-ester and asymmetrically substatuted di-ester pro-drugs of dopamide D1 receptor agonists
US7220754B2 · kind B2 · utility
5Cited by
6References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 14, 2003 |
| Grant date | May 22, 2007 |
| Priority date | — |
| Expiry date | Mar 24, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D221/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Mono-ester and asymmetrically substituted diesters of dihydrexidine, dinapsoline and A-86929 and substituted derivatives thereof are described. The novel ester/diester derivatives exhibit improved pharmacokinetic characteristics relative to their unesterified parent compounds and can be formulated into pharmaceutical compositions useful for the treatment of a wide variety of dopamine related disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.