Patent · US Expired

Methods and apparatus for isolating platelets from blood

US7223346B2 · kind B2 · utility

148Cited by
58References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 18, 2005
Grant dateMay 29, 2007
Priority date
Expiry dateJun 28, 2025

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/25375
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Platelets are then removed from the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.