Proteasome inhibitors and methods of using the same
US7223745B2 · kind B2 · utility
12Cited by
30References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 12, 2004 |
| Grant date | May 29, 2007 |
| Priority date | — |
| Expiry date | May 27, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.