Nucleic acids encoding glial cell line-derived neurotrophic factor (GDNF)
US7226758B1 · kind B1 · utility
30Cited by
20References
33Claims
0Family size
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Key dates
| Filing date | Sep 17, 1992 |
| Grant date | Jun 5, 2007 |
| Priority date | — |
| Expiry date | Sep 17, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/839
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel neurotrophic factor referred to as glial cell line-derived neurotrophic factor (GDNF) has been identified and isolated from serum free growth conditioned medium of B49 glioblastoma cells. Rat and human genes encoding GDNF have been cloned and sequenced. A gene encoding GDNF has been subcloned into a vector, and the vector has been used to transform a host cell in order to produce biologically active GDNF in a recombinant DNA process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.