NF-κB activating gene
US7227007B2 · kind B2 · utility
7Cited by
1References
11Claims
0Family size
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Key dates
| Filing date | Jul 11, 2003 |
| Grant date | Jun 5, 2007 |
| Priority date | — |
| Expiry date | Apr 21, 2024 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A90/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided are proteins having NF-κB activity, which are used for diagnosing, treating or preventing diseases associated with the excessive activation or inhibition of NF-κB. Using plasmid pNFκB-Luc, cDNA encoding a protein capable of activating NF-κB has been cloned from a cDNA library constructed from human lung fibroblasts, and the DNA sequence and the deduced amino acid sequence determined. The protein, the DNA encoding the protein, a recombinant vector containing the DNA, and a transformant containing the recombinant vector are useful for screening a substance inhibiting or promoting NF-κB activation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.