Growth differentiation factor-9 regulatory sequences and uses therefor
US7227013B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 31, 1999 |
| Grant date | Jun 5, 2007 |
| Priority date | — |
| Expiry date | Mar 31, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/47
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Isolated GDF-9 regulatory sequences are disclosed, as well as methods of using the sequences to modulate tissue-specific expression of genes. The GDF-9 regulatory sequences include, for example, enhancer and promoter elements that naturally drive transcription of GDF-9 in specific tissues. The GDF-9 regulatory sequences can be derived from the untranscribed upstream (e.g., first 10 kilobases) and downstream regions, and transcribed, untranslated regions of a GDF-9 gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.