Method for the synthesis of a benzimidazole compound
US7227024B2 · kind B2 · utility
1Cited by
6References
16Claims
0Family size
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Inventor
Key dates
| Filing date | Oct 15, 2003 |
| Grant date | Jun 5, 2007 |
| Priority date | — |
| Expiry date | Jan 29, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the manufacture of omeprazole or esomeprazole from pyrmethyl alcohol via pyrmethyl chloride and pyrmetazole characterized in that the whole reaction sequence is carried out without any isolation or purification of intermediates. Further, the reaction is carried out in a solvent system common for the whole reaction sequence and inert to the reactants formed during the process and used in the process and comprises a water immiscible organic solvent and a specified amount of water.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.