Synthesis of irbesartan
US7227026B2 · kind B2 · utility
1Cited by
6References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 6, 2006 |
| Grant date | Jun 5, 2007 |
| Priority date | — |
| Expiry date | Feb 6, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Provided are a method of making irbesartan via a Suzuki coupling reaction and a novel intermediate, 2-butyl-3-(4′-bromobenzyl)-1,3-diazaspiro[4.4]non-1-ene-4-one, for such process. The novel process includes the step of reacting such intermediate with a protected imidazolephenylboronic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.