Compounds displayed on icosahedral phage and methods of using same
US7229757B2 · kind B2 · utility
6Cited by
12References
26Claims
0Family size
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Key dates
| Filing date | Mar 21, 2002 |
| Grant date | Jun 12, 2007 |
| Priority date | — |
| Expiry date | Oct 24, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6845
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Icosahedral phage and collections thereof that display various compounds are provided. In some instances, the icosahedral phage include nucleic acid tags that serve to record a characteristic of the compound or compounds that are attached to the phage. A number of different methods for using the icosahedral phage to screen a library of compounds for a desired biological activity are also provided, especially assays for compounds that are substrates for receptor-mediated transport processes such as endocytosis and transcytosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.