Protease susceptibility II
US7229788B1 · kind B1 · utility
1Cited by
4References
23Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 19, 1999 |
| Grant date | Jun 12, 2007 |
| Priority date | — |
| Expiry date | Jul 19, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to: manipulation of the amino acid sequence of tropoelastin, particularly human tropoelastin, to modify its protease susceptibility; to tropoelastin derivatives having modified protease susceptibility; to peptidomimetic molecules which contain amino acid sequences which correspond to or incorporate the protease susceptible sequences of tropoelastin; and to uses of the tropoelastin derivatives and peptidomimetic molecules.The invention also relates to nucleic acid molecules and genetic constructs encoding the amino acid sequences of the derivatives and peptidomimetic molecules of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.