Methods for the synthesis of lactic acid using crabtree-negative yeast transformed with the lactate dehydrogenase gene

US7229805B2 · kind B2 · utility

Assignee

• Nature Work, LLP · US

Inventors

• Vineet Rajgarhia · Dublin, US
• Vassily Hatzimanikatis · Minneapolis, US
• Stacey Olson · Minneapolis, US
• Ting Liu Carlson · Dayton, US
• John N. Starr · Chaska, US
• Jeffrey John Kolstad · Wayzata, US
• Aharon Eyal · Jerusalem, IL

Key dates

• Filing date: Nov 4, 2002
• Grant date: Jun 12, 2007
• Expiry date: Jun 14, 2023

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02E50/10
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention provides methods and materials related to the production of lactic acid. Specifically, the invention provides methods for producing lactic acid using a crabtree-negative yeast, such as of the Kluyveromyces, Pichia, Candida, Trichosporon and Yamadazmya genera, which have been transformed with a lactate dehydrogenase gene.