Rifamycin derivatives
US7229996B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 21, 2005 |
| Grant date | Jun 12, 2007 |
| Priority date | — |
| Expiry date | Sep 25, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D455/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel rifamycin derivatives of formula I (both hydroquinone and corresponding quinone (C1-C4) forms):or their salts, hydrates or prodrugs thereof,wherein: a preferred R comprises hydrogen, acetyl; L is a linker, a preferred linker group elements selected from any combination of 1 to 5 groups shown FIG. 1, provided L is notwherein R1 is H, methyl or alkyl. The inventive compounds exhibit valuable antibiotic properties. Formulations having these compounds can be used in the control or prevention of infectious diseases in mammals, both humans and non-humans. In particular, the compounds exhibit a pronounced antibacterial activity, even against multiresistant strains of microbes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.