Immobilization of oligonucleotides onto solid supports
US7230095B2 · kind B2 · utility
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4References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 25, 2002 |
| Grant date | Jun 12, 2007 |
| Priority date | — |
| Expiry date | Dec 15, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A solid support bound polynucleotide, preferably a 3′-O- or 5′-O-substituted polynucleotide, is disclosed. The polynucleotides are of formula:wherein Q is a substantially pure polynucleotide, each X is O or S; Y is an inert spacer group; R represents the solid support. Also disclosed is a method of isolating a target biomolecule, preferably a protein or a polynucleotide, from a mixture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.