Aminoheteroaryl compounds as protein kinase inhibitors

US7230098B2 · kind B2 · utility

Assignee

• Sugen, Inc. · US

Inventors

• Jingrong Jean Cui · San Diego, US
• Dilip Bhumralkar · Valencia, US
• Iriny Botrous · San Diego, US
• Ji Yu Chu · Fremont, US
• Lee Andrew Funk · Oceanside, US
• Cathleen Hanau · Chesterfield, US
• G. Davis Harris, Jr. · San Francisco, US
• Lei Jia · Palo Alto, US
• Joanne Johnson · Guilderland, US
• Stephen Kolodziej · Ballwin, US
• Pei-Pei Kung · San Diego, US
• Xiaoyuan Li · Los Altos, US
• Jason (Qishen) Lin · San Diego, US
• Jerry Jialun Meng · San Diego, US
• Mitchell David Nambu · San Diego, US
• Christopher Nelson · Bear, US
• Mason Alan Pairish · San Diego, US
• Hong Shen · Shanghai, CN
• Michelle Tran-Dube · Village of La Jolla, US
• Allison Walter · Rexford, US
• Fang-Jie Zhang · Sunnyvale, US
• Jennifer R. Zhang · Union City, US

Key dates

• Filing date: Feb 26, 2004
• Grant date: Jun 12, 2007
• Expiry date: Mar 1, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET