Heterocyclic inhibitors of MEK and methods of use thereof
US7230099B2 · kind B2 · utility
17Cited by
4References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 30, 2004 |
| Grant date | Jun 12, 2007 |
| Priority date | — |
| Expiry date | Aug 30, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D261/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compounds of the Formulaand pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8, R9 and R10, W and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.