Agent delivery systems
US7232421B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 12, 2000 |
| Grant date | Jun 19, 2007 |
| Priority date | — |
| Expiry date | May 12, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2018/00392
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention provides a system for delivering a therapeutic agent into tissue in combination with an implant device (2). Preferably the therapeutic substance is contained within a pellet form (14) that is deliverable into the interior of the device (2) after it has been implanted. In a preferred embodiment the implant device (2) comprises a flexible coiled spring body, the coils (4) of which have the proper diameter and spacing to contain the pellet (14) within the interior of the device (2) to contact the therapeutic agent. In treatment of ischemic tissue such as that of the myocardium of the heart, the mechanical irritation of the tissue caused by the implanted device (2) can help to provide an angiogenic effect. Additionally, the cavity (18) provided by the interior of the device (2) permits blood to pool around the pellet (14) and mix with the therapeutic agent. Several delivery systems have provided for delivering the implant and pellet (14) sequentially or simultaneously.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.