Patent · US Expired

Antibodies against tumor surface antigens

US7232888B2 · kind B2 · utility

13Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 1, 2003
Grant dateJun 19, 2007
Priority date
Expiry dateApr 28, 2024

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/622
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to improved antibodies against tumor surface antigens and their use in the treatment of tumors. Of particular interest are highly stable, humanized, high affinity antibodies against carcinoembryonic antigen (CEA), especially the antibody we have termed sm3E, which is derived from the scFv antibody MFE-23. Such antibodies have the potential for improved therapeutic efficacy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.