Preparation and use of diols
US7232933B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Apr 29, 2002 |
| Grant date | Jun 19, 2007 |
| Priority date | — |
| Expiry date | Nov 27, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of diols by a Lewis acid-catalysed aldehyde addition reaction on hydroxyalkynes followed by hydrogenation is described. The process provides a wide range of diols from simple, readily available starting materials. In particular the process is suitable for preparing chiral 1,4-diols suitable for the preparation of chiral phospholane ligands for use in asymmetric catalysis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.