Predicting hepatotoxicity using cell based assays
US7235353B2 · kind B2 · utility
7Cited by
37References
19Claims
0Family size
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Key dates
| Filing date | Jul 18, 2003 |
| Grant date | Jun 26, 2007 |
| Priority date | — |
| Expiry date | Feb 21, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N1/30
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the stimulus on the basis of whether it is hepatotoxic, and if so what type of pathology is exhibited; e.g., apoptosis, necrosis, cholestasis, and/or steatosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.