Method for determining cell cycle position
US7235401B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 12, 2002 |
| Grant date | Jun 26, 2007 |
| Priority date | — |
| Expiry date | Sep 12, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/63
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides a novel, non-destructive and dynamic process for determining the cell cycle position of living cells. The invention also provides DNA constructs, and cell lines containing such constructs, that exhibit activation and deactivation of a detectable reporter molecule in a cell cycle specific manner. The invention thus allows greater precision in determining cell cycle phase status than existing techniques and further provides a method for continuous monitoring of cell cycle progression in individual cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.