Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV
US7235538B2 · kind B2 · utility
89Cited by
9References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 17, 2003 |
| Grant date | Jun 26, 2007 |
| Priority date | — |
| Expiry date | Jul 17, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV, which are of formula Iwherein each n is one or two independently and R1, R2, R3, R6, R7, R9, and R10 are defined herein. The present invention also relates to pharmaceutical compositions comprising the compounds of formula I and the use of the compounds for treating diseases that are associated with proteins that are subject to inactivation by DPP-IV, such as type-2 diabetes and obesity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.