Patent · US Expired

Bispecific antibodies

US7235641B2 · kind B2 · utility

77Cited by

5References

2Claims

0Family size

Assignee

Micromet AG · DE

Inventors

Peter Kufer · Munich, DE
Meera Berry · Ulm, DE
Patrick Baeuerle · Gauting, DE
Christian Itin · Menlo Park, US

Key dates

Filing date	Dec 22, 2003
Grant date	Jun 26, 2007
Priority date	—
Expiry date	Sep 30, 2024

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2830/48
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention discloses bispecific antibodies comprising two antibody variable domains on a single polypeptide chain, wherein a first portion of the bispecific antibody is capable of recruiting the activity of a human immune effector cell by specifically binding to an effector antigen on the human immune effector cell, the first portion consisting of one antibody variable domain, and a second portion of the bispecific antibody specifically binding to a target antigen other than the effector antigen, the target antigen on a target cell other than the human immune effector cell, the second portion comprising one antibody variable domain.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.