Alpha 2HS glycoprotein for treatment of cancer and a method for preparation thereof
US7238662B2 · kind B2 · utility
1Cited by
12References
3Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 8, 2002 |
| Grant date | Jul 3, 2007 |
| Priority date | — |
| Expiry date | Jan 18, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention characterizes the selective apoptotic activity of specially prepared Alpha 2-HS glycoprotein and fragments thereof. Specifically, Alpha 2-HS glycoprotein which has been overloaded with zinc, as well as fragnents thereof, selectively induce apoptosis in HT-29 (colon cancer), LNCaP (prostate cancer) and Hep G2 (hepatoma) cells while having no effect on CCD 18 Co (normal colon) cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.