Piperidine derivatives and their use as modulators of chemokine (especially CCR3) activity
US7238691B2 · kind B2 · utility
4Cited by
10References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 12, 2002 |
| Grant date | Jul 3, 2007 |
| Priority date | — |
| Expiry date | Apr 25, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides a compound of formula (I): T is C(O) or S(O)2; W is CH2, (CH2)2, CH(CH3), CH(CH3)O or cyclopropyl; X is O, CH2, C(O), S, S(O), S(O)2 or NR3; m is 0 or 1; R1 is optionally substituted aryl or optionally substituted heterocyclyl; R2 is alkyl (optionally substituted by OH), cycloalkyl, optionally substituted aryl or optionally substituted heterocyclyl; that are modulators of chemokine (especially CCR3) activity and are especially useful for treating asthma and/or rhinitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.