Frame-shifting PCR for germline immunoglobulin genes retrieval and antibody engineering
US7241598B2 · kind B2 · utility
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3References
19Claims
0Family size
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Key dates
| Filing date | Jun 29, 2004 |
| Grant date | Jul 10, 2007 |
| Priority date | — |
| Expiry date | Dec 4, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/622
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for preparing an antigen-specific antibody by constructing a library of phage-displayed single chain variable fragment of an antibody with a novel frame-shifting PCR is disclosed. Also disclosed is a method for preparing a clone for producing an antigen-specific antibody.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.