Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines

US7241775B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Armin Hofmeister · Frankfurt, DE
• Uwe Heinelt · Wiesbaden, DE
• Hans-Jochen Lang · Hofheim, DE
• Wendelin Frick · Bad Camberg, DE
• Markus Bleich · Brechen, DE
• Klaus Wirth · Frankfurt am Main, DE

Key dates

• Filing date: Mar 24, 2004
• Grant date: Jul 10, 2007
• Expiry date: Mar 14, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D217/22
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Substituted 4-phenyltetrahydroisoquinolines of formula I, process for their preparation, their use as a medicament and medicaments containing them.The compounds of formula I can be used, among other uses, in the event of renal disorders such as acute or chronic renal failure, in the event of disorders of biliary function, in the event of respiratory disorders such as snoring or sleep apneas or in the event of stroke.