Compositions and methods for the therapy and diagnosis of breast cancer

US7241876B2 · kind B2 · utility

Assignee

• CORIXA CORPORATION · US

Inventors

• Tony Frudakis · Sarasota, US
• Steven G. Reed · Bellevue, US
• John M. Smith · Everett, US
• Lynda Misher · Seattle, US
• Davin C. Dillon · Issaquah, US
• Marc Retter · Carnation, US
• Aijun Wang · Davis, US
• Yasir Skeiky · Bellevue, US
• Susan Harlocker · Foster City, US
• Craig Day · Seattle, US
• Samuel X. Li · Redmond, US
• Ta Deng · Edmonds, US

Key dates

• Filing date: Aug 7, 2001
• Grant date: Jul 10, 2007
• Expiry date: Aug 7, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.