Methods for the preparation, isolation and purification of epothilone B, and X-ray crystal structures of epothilone B
US7241899B2 · kind B2 · utility
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Key dates
| Filing date | Mar 22, 2004 |
| Grant date | Jul 10, 2007 |
| Priority date | — |
| Expiry date | Sep 7, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to improved methods for the production, isolation and purification of epothilone B. These methods include, for example, a fermentation process for the production of epothilone B, isolation via adsorption onto a resin, and subsequent purification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.