Method of sequencing a nucleic acid

US7244559B2 · kind B2 · utility

Assignee

• 454 Life Sciences Corporation · US

Inventors

• Jonathan M. Rothberg · Paradise, US
• Joel S. Bader · Stamford, US
• Scott Dewell · New Haven, US
• Keith McDade · Higganum, US
• John W. Simpson · Madison, US
• Jan Berka · New Haven, US
• Christopher Colangelo · Old Lyme, US

Key dates

• Filing date: Mar 21, 2001
• Grant date: Jul 17, 2007
• Expiry date: Mar 21, 2021

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2300/0893
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.