Use of molecular chaperones for the enhanced production of secreted, recombinant proteins in mammalian cells
US7244616B2 · kind B2 · utility
8Cited by
9References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Mar 3, 2004 |
| Grant date | Jul 17, 2007 |
| Priority date | — |
| Expiry date | Mar 3, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.