Patent · US Active

Tubulin inhibitor and process for its preparation

US7244736B2 · kind B2 · utility

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47Claims
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Inventors

Key dates

Filing dateJun 12, 2006
Grant dateJul 17, 2007
Priority date
Expiry dateJun 12, 2026

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention provides 6-chloro-5-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-2-pyrazin-2-yl-N-[(1S)-2,2,2-trifluoro-1-methylethyl]pyrimidin-4-amine hemifumarate which is a tubulin inhibitor useful in the treatment of cancer and processes of making hemifumarate compounds and compositioning of the present invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.