Methods for preparation and use of psorospermin analogs
US7244760B2 · kind B2 · utility
1Cited by
1References
6Claims
0Family size
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Key dates
| Filing date | May 20, 2002 |
| Grant date | Jul 17, 2007 |
| Priority date | — |
| Expiry date | Jul 23, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Psorospermin is a cytotoxic dihydroflranoxanthone that has found to exhibit significant activity against various tumor cell lines. Unfortunately, psorospermin is no longer readily available from its natural plant source. The present invention is directed to a method for preparing psorospermin and psorospermin analogs. Methods are also disclosed for utilizing psorospermin analogs to inhibit cellular proliferation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.