Patent · US Expired

Methods of treating using anti-IL-15 antibodies

US7247304B2 · kind B2 · utility

17Cited by
8References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 5, 2003
Grant dateJul 24, 2007
Priority date
Expiry dateAug 11, 2024

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/73
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Isolated human monoclonal antibodies which specifically bind to IL-15 (e.g., human IL-15), and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced in a transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals, and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.