Patent · US Expired

Anticalins

US7250297B1 · kind B1 · utility

102Cited by

2References

5Claims

0Family size

Assignee

Pieris AG · DE

Inventors

Gerald Beste · Munich, DE
Thomas Stibora · Michendorf, DE
Arne Skerre · Freising, DE
Frank Schmidt · Zorneding, DE

Key dates

Filing date	Sep 25, 1998
Grant date	Jul 31, 2007
Priority date	—
Expiry date	Sep 25, 2018

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2799/021
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to the production of novel proteins exhibiting bonding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using genetic engineering methods. A like immunoglobulin, the anticalin thus obtained can be used to identify or bond molecular structures.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.