Compositions and methods for the acceleration of protein secretion dynamics
US7250406B2 · kind B2 · utility
4Cited by
1References
55Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 21, 2003 |
| Grant date | Jul 31, 2007 |
| Priority date | — |
| Expiry date | Nov 12, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/63
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods for modulating the secretion of transcriptionally regulated proteins from recombinant cells. More particularly, the present invention provides compositions and methods for accelerating the secretion dynamics of human insulin from recombinant cells using nonsense mediated mRNA decay of the preproinsulin mRNA transcript.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.