Tetrazole and oxadiazolone substituted β-amino acid derivatives
US7250433B2 · kind B2 · utility
3Cited by
4References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 8, 2004 |
| Grant date | Jul 31, 2007 |
| Priority date | — |
| Expiry date | Sep 1, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D271/07
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel tetrazole and oxadiazalone β-amino acids derivatives of the formulawherein G iswherein R1 through R4 are defined as in the specification, pharmaceutical compositions containing them and their use for the treatment of various central nervous system and other disorders. The cyclopropyl β-amino acids derivatives of this invention exhibit activity as alpha2delta ligands (α2δ ligands). Such compounds have affinity for the α2δ subunit of a calcium channel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.