Bioinformatically detectable group of novel regulatory genes and uses thereof
US7250496B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 6, 2002 |
| Grant date | Jul 31, 2007 |
| Priority date | — |
| Expiry date | Nov 19, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B15/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The present invention relates to a first group of novel genes, here identified as “genomic address messenger” or “GAM” genes, and a second group of novel operon-like genes, here identified as “genomic record” or “GR” genes. GAM genes selectively inhibit translation of known ‘target’ genes, many of which are known to be involved in various diseases. Nucleic acid molecules are provided respectively encoding 20600 GAM genes, and 6635 GR genes, as are vectors and probes both comprising the nucleic acid molecules, and methods and systems for detecting GAM and GR genes and specific functions and utilities thereof, for detecting expression of GAM and GR genes, and for selectively enhancing and selectively inhibiting translation of the respective target genes thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.