Patent · US Expired

Cancerous disease modifying antibodies

US7252821B2 · kind B2 · utility

5Cited by
14References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 23, 2003
Grant dateAug 7, 2007
Priority date
Expiry dateDec 5, 2024

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2039/505
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.