Methods and compositions for modulating cell proliferation
US7252944B2 · kind B2 · utility
0Cited by
1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 30, 2004 |
| Grant date | Aug 7, 2007 |
| Priority date | — |
| Expiry date | Sep 15, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention provides methods for identifying novel SHMT modulators. The methods comprise first screening test agents for modulators of p38 activity and then further screening the identified modulating agents for modulators of SHMT enzyme activity. The invention further provides methods and pharmaceutical compositions for modulating cellular proliferation and for treating tumors using the novel SHMT modulators.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.