Method of detecting and preventing Alzheimer's disease, particularly at prodromal and early stages
US7252953B2 · kind B2 · utility
1Cited by
1References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 12, 2003 |
| Grant date | Aug 7, 2007 |
| Priority date | — |
| Expiry date | Aug 12, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2821
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of detecting Alzheimer's disease includes detecting a disruption or alteration in normal sub-cellular distribution of G-protein receptor kinases (GRKs), particularly GRK2 and GRK5. The disruption is caused by abnormal accumulation of soluble β-amyloid. The prevention or suppression of the disease progression at prodromal or early stages includes correction of GRK dysfunction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.