Compounds and inhibitors of phospholipases

US7253194B2 · kind B2 · utility

Assignee

• The University Of Queensland · AU

Inventors

• Robert C. Reid · Calle de la Era, AU
• Christopher Clark · Brisbane, AU
• Karl Hansford · Brisbane, AU
• Martin J Stoermer · Maitland, AU
• Ross Peter McGeary · Brisbane, AU
• David Fairlie · Faulconbridge, AU
• Karl Schafer · Leverkusen, DE

Key dates

• Filing date: Jul 24, 2001
• Grant date: Aug 7, 2007
• Expiry date: Apr 12, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/4075
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates generally to amino acid derivatives and to methods of making the same. In particular, the invention relates to compounds bearing a stereochemical identity, that is, the same stereochemistry, with the chiral α-carbon of D-α-amino acids and their use in methods of therapy, including the treatment of inflammatory diseases, and to compositions and enantiomeric mixtures containing them.