Monoclonal antibodies against the epitope YPYDVPDYA, a process for their production and their use

US7255859B1 · kind B1 · utility

Assignee

• Roche Diagnostics GMBH · DE

Inventors

• Thomas Emrich · Iffeldorf, DE
• Matthias Hinzpeter · Hersbruck, DE
• Michael Grol · Feldafing, DE

Key dates

• Filing date: Oct 20, 1997
• Grant date: Aug 14, 2007
• Expiry date: Oct 20, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K16/1018
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention concerns monoclonal antibodies against the epitope YPYDVPDYA (SEQ ID NO: 1) which is derived from the haemagglutinin of the human influenza virus and are suitable for the detection and isolation of native haemagglutinin of the human influenza virus, of modified haemagglutinin or of haemagglutinin fusion proteins and have an affinity of >108 M−1, in particular of 109 to 1010 M−1.