Transfection complexes

US7256043B2 · kind B2 · utility

Assignee

• ICH Productions Limited · GB

Inventors

• Stephen Hart · London, GB
• Michele Writer · Cambridge, GB

Key dates

• Filing date: Mar 14, 2002
• Grant date: Aug 14, 2007
• Expiry date: Feb 27, 2023

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides a peptide having at least 3 amino acids comprising an amino acid sequence selected from a) X1SM [SEQ.ID.NO.:1] b) LX2HK [SEQ.ID.NO.:2] c) PSGX3ARA [SEQ.ID.NO.:9] d) SX4RSMNF [SEQ.ID. NO.:16] e) LX5HKSMP [SEQ.ID.NO.:18] in which X is a basic amino acid residue, X1 is Q or P, X2 is A or T, X3 is an acidic amino acid residue and X4 is P or Q, the invention further provides non-viral cell-targeting vector complexes and methods associated therewith.