Patent · US Active

3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone der derivatives as protein kinase inhibitors

US7256189B2 · kind B2 · utility

2Cited by

81References

2Claims

0Family size

Assignees

Sugen, Inc. · US
Pharmacia & Upjohn Company LLC · US

Inventors

Huiping Guan · Shanghai, CN
Congxin Liang · North Palm Beach, US
Li-Qiang Sun · Foster City, US
Peng Cho Tang · Moraga, US
Chung Chen Wei · Cedar Knolls, US
Tomas Vojkovsky · North Palm Beach, US
Qingwu Jin · Kalamazoo, US
Paul Herrinton · Novi, US
Michael Mauragis · Scotts, US

Key dates

Filing date	Aug 28, 2006
Grant date	Aug 14, 2007
Priority date	—
Expiry date	Aug 28, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.